The setting-up of temporary exhibitions and museums requires careful design of spaces and an arrangement of works curated in every single detail for offering the public an engaging and memorable experience. Communication within the museum must use different types of language to allow each visitor to decode the exhibited works and interpret them according to their own cultural and experiential background. In addition to information on the works on display, museum signage must also provide indications on the visitor’s itinerary so that everyone can adjust it to their liking by selecting the artists or themes of greatest interest. Finally, the areas dedicated to reception (refreshment and relaxation areas, shops and ticket offices) should not be neglected; in addition to having an important functional role, they improve the experience inside the exhibition space, allowing the visitor to recover the physical and mental energy necessary for continuing the visit. In order to best combine teaching and functional needs, museum setting-up calls for differentiated and complementary expertise, including visual and multimedia communication, museography, lighting and interior design. Those who set up an exhibition should consider these aspects for making the most of the exhibition space and offering the public an interesting and educational experience. With this in mind, it is important not only to provide clear and easily understandable information on the individual works on display, but to offer interpretative keys that allow the visitor to build a broader overall view. In this sense, the written word used in captions, on information panels and in paper guides can be supplemented by different and complementary forms of communication. Architectural elements designed ad hoc, audio installations, interactive multimedia devices and augmented reality applications can promote a multi-sensory and participatory learning process. Thanks to its many years of experience in setting up cultural events and exhibition venues of great prestige and international relevance, Tosetto is able to provide a complete and customised turnkey service for designers and planners of museum spaces and exhibitions seeking an experienced and reliable partner.